Operated by Southeastern Stages and Greyhound USA, the Raleigh to Myrtle Beach bus service departs from Raleigh and arrives in Myrtle Beach, …Are you dreaming of a relaxing beach getaway? Look no further than North Myrtle Beach, South Carolina. This includes an average layover time of around 1h. The bus journey time between Raleigh and Myrtle Beach is around 5h 25m and covers a distance of around 224 miles.